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Ohio State researchers demonstrate that PDGF-BB transforms vascular pericytes into axon-supporting bridges, offering a promising strategy for spinal cord repair.
Ohio State Unveils Breakthrough in Spinal Cord Repair
Reprogramming Pericytes for Neural Regeneration
In a groundbreaking study published in the journal Molecular Therapy, researchers at The Ohio State University have explored a novel strategy for spinal cord repair that utilizes the body’s own cells. This research focuses on the manipulation of pericytes, specialized cells located in the blood vessels, to promote nerve regeneration following spinal cord injuries.
Overview of Spinal Cord Injuries
Spinal cord injuries can lead to devastating consequences, including loss of mobility and sensation. The injury not only disrupts the transmission of signals between the brain and the body, but it also severely compromises the vascular structures surrounding the injury site. This dual disruption complicates recovery and limits the effectiveness of potential treatments.
