Machine-phase medicine
Nanomatter, or: Self-assembling bioreactor-mechanotransistor arrays for molecular engineering and programmable matter
We can and will cure all diseases. My dad died of a heart attack the day I was scheduled to dissect the human heart in med school anatomy.
My name’s Bion and I’m a Molecular Biologist. I won’t give up until I’m dead.
Cures require delivery. What better than to print the cure inside the body?
I wrote this patent with Kent Kemmish in 2015 for Universal Molecular, now bitpharma.com. Rathna Kumar helped turn my sketches into Autocad models.
The idea is to use some to read and write molecules inside our body.
The patent is incomplete because I didn’t have the time, money and FOCUS to finish such a huge and expensive project — but I pray that one day it will save lives and improve human health.
Inventors, understand: ideas are just the first step in a larger journey…
Want to help? The project is open source under an MIT license.
I’m happy to collaborate… email bion at bitpharma.com
Field:
The present invention pertains to nanotechnology and molecular engineering.
Abstract:
The present invention is a 3D selfassembling array of hollow selfassembling polyhedral bioreactors in which each face of each polyhedron contains a multilayer electromechanical circuit. Each circuit includes a mechanotransistor, or mechanical aperture, an opening with controllable size and shape that controls fluid flow into and through the array. Mechanotransistors include electrode stacks surrounding the aperture which monitor current flow. Structures passing through these pores cause deviations in current flow in proportion to their electronic characteristics and crosssectional area, providing useful data for molecular analytics. Circuitry on faces of the polyhedra contains numerous additional elements relevant to energy harvesting and storage, navigation, computation, communication, sensing, actuation, and molecular engineering (e.g. manufacturing biomacromolecules). By combining numerous sensor technologies and multiplexing analysis over large numbers of bioreactors, such arrays perform highly accurate universal molecular analysis, identifying the full spectrum of constituents within desired fluids. These bioreactor arrays can programmatically assemble and disassemble into desired shapes using electropermanent magnets within the polyhedral face circuitry. At sufficiently low density and size, bioreactors can fly via a piezoelectric mechanism similar to a beating heart, pulling in fluid above them and pumping it out below, controlling flow using mechanotransistors as dynamic valves. An array of bioreactors could be controlled using radio waves or voice control using piezo and accelerometer sensing.The use of biocompatible materials and self-destruction minimizes or eliminates harmful effects to natural ecosystems. Large quantities of non-replicating bioreactors can be manufactured using roll-to-roll nano-imprint lithography. Thus, the present invention, also named, “nanomatter,” is useful as a type of programmable matter which performs molecular engineering, enabling scalable production of arbitrary form factors capable of spatiotemporal analysis and control of biological systems on the nanoscale.
Related Art:
Current techniques for molecular engineering are bulky, expensive, and overspecialized.
potential future improvements:
magnetohydrodynamic propulsion
photonic molecular printing
nanochannel sensing
agi
Copyright 2015–2018 Bion Howard and Stanley “Kent” Kemmish
Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the “Software”), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions:
The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software.
THE SOFTWARE IS PROVIDED “AS IS”, WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE.
