Get that memory moving
A technique to “tag” motor memories could help to treat movement disorders and improve athletic performance.
Memory is strongly affected by the context in which a particular memory is formed and remembered. For example, visiting a familiar place can often trigger memories associated or “tagged” with that place. Such tagging also exists for memories related to movement: for instance, distinct motor memories for a limb movement are formed depending on whether the other limb is stationary or moving. However, little is known about how the tagging of such motor memories takes place.
Daichi Nozaki and colleagues have now used a technique known as transcranial direct current stimulation to generate artificial “tags” for motor memories. In the experiments, volunteers tried to move a robotic arm towards a goal while the robot pushed their hand off-course. Sometimes the robot pushed the participant’s hand to the left, and sometimes to the right. This makes the task difficult to learn, even when the cue for the direction is provided, as the motor memories that are made to counteract each push overwrite each other.
Nozaki and colleagues used transcranial stimulation to alter the background electrical activity in the sensorimotor regions of the participants’ brains as they performed the robotic arm task. Artificially generating a different pattern of background brain electrical activity for each push direction caused the motor memories associated with leftward and rightward pushes to be tagged differently. Once this association had been learnt, applying the artificial brain stimulation pattern associated with one of the pushes resulted in the participants unconsciously compensating for a push in that direction, even when it was not there.
Overall, the results presented by Nozaki and colleagues suggest that the background electrical activity seen in the brain can influence how a motor memory is created and later recalled. A future challenge is to investigate whether this technique could be used to help athletes improve their performance or to treat people with movement disorders. Further experiments are also needed to test whether the same approach can influence the formation and recollection of other kinds of memories, such as those related to fear.
To find out more
Read the eLife research paper on which this eLife digest is based: “Tagging motor memories with transcranial direct current stimulation allows later artificially-controlled retrieval” (July 29, 2016).
