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A promising new vaccine candidate could protect us from multiple coronaviruses — including some that haven’t jumped to humans yet

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The “pancoronavirus” vaccine technology has been tested in monkeys so far. It could mean coronavirus shots won’t have to be given seasonally.

A nurse prepares the Pfizer-BioNTech COVID-19 vaccine in London in December 2020.
A nurse prepares the Pfizer-BioNTech COVID-19 vaccine in London in December 2020. Photo: Frank Augstein/AP

By Aria Bendix

Current coronavirus vaccines were designed to protect us from one particular coronavirus: SARS-CoV-2, the virus responsible for this pandemic.

But the coronavirus family is large, and many researchers think a future vaccine could offer far broader protection.

A team at the Duke Human Vaccine Institute has developed a pancoronavirus vaccine that might be able to protect against multiple coronaviruses in the SARS family. That includes SARS-CoV-2, as well as the virus most people know as SARS — SARS-CoV-1 — which was responsible for an outbreak in 2003.

In a new study, the Duke team’s vaccine candidate was found to protect rhesus monkeys from the new coronavirus (including its most concerning variants), as well as SARS and other SARS-related viruses that circulate in bats but haven’t jumped to humans. That’s an indicator, though by no means a guarantee, that the vaccine might also work in people.

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