Metformin For Weight Loss? Is It Possible?

Damin Lee
Change Your Mind Change Your Life
4 min readJun 9, 2023
Photo by Sweet Life on Unsplash

Metformin is a medicine used to treat type 2 diabetes and gestational diabetes.‍

Are you struggling with weight loss despite trying your hardest?

If you are...

Consider adding metformin to your weight loss regimen!

Metformin is a safe medication for treating diabetes but also has weight loss-inducing properties.

Before you try it, you need to make sure you know what it is. So keep reading!

What is Metformin?

Metformin is an oral medication that’s been used to treat type 2 diabetes for over 60 years.

It works by lowering the amount of glucose the liver produces and improving insulin sensitivity, which helps the body use insulin more effectively.

By reducing insulin resistance, metformin helps to lower blood sugar levels in people with type 2 diabetes.

Metformin is typically prescribed in doses of 500mg to 2,000mg daily, taken in divided doses with meals.

It’s available under brand names such as Glucophage, Glumetza, and Fortamet.

How Does Metformin Aid in Weight Loss?

While metformin was originally developed to treat diabetes, recent studies have shown that it can also aid in weight loss.

One way metformin can help with weight loss is by reducing appetite.

A study published in the Diabetologia journal found that metformin reduced food intake and hunger in obese individuals with type 2 diabetes.

Another way metformin can help with weight loss is by improving insulin sensitivity.

Insulin is a hormone that regulates blood sugar levels and helps the body store fat. When the body becomes insulin-resistant, losing weight’s more difficult.

Metformin improves insulin sensitivity, helps the body use insulin more effectively, and promotes weight loss.

Metformin has also been found to improve lipid profiles, decrease inflammation, and potentially reduce the risk of certain cancers.

A study published in the journal Cancer Prevention Research found that metformin reduced the risk of developing pancreatic cancer in individuals with type 2 diabetes.

Photo by Diana Polekhina on Unsplash

Dosage and Administration of Metformin for Weight Loss

If you’re considering using metformin for weight loss, speaking with your doctor first is important.

They can help determine if metformin is right for you and what dosage to take. Generally, metformin is prescribed in doses of 500mg to 2,000mg daily, taken in divided doses with meals.

It’s important to take metformin as directed by your doctor and not to exceed the recommended dosage. Too much metformin can cause serious side effects, including lactic acidosis, a buildup of lactic acid in the blood.

Possible Side Effects of Metformin

Like any medication, metformin can cause side effects. Common side effects of metformin include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Loss of appetite
  • Headache
  • Metallic taste in the mouth

In rare cases, metformin can cause a serious side effect called lactic acidosis, which is a buildup of lactic acid in the blood. Lactic acidosis can be life-threatening and requires immediate medical attention. Symptoms of lactic acidosis include:

  • Nausea
  • Vomiting
  • Abdominal pain
  • Muscle weakness
  • Rapid breathing
  • Dizziness
  • Confusion
  • Coma

If you experience any of these symptoms while taking metformin, seek medical attention immediately.

Metformin and Lifestyle Changes for Weight Loss

While metformin can aid in weight loss, combining it with healthy lifestyle changes is important for maximum effectiveness.

This includes eating a healthy diet, regular exercise, and enough rest.

Regarding diet, focus on eating whole, nutrient-dense foods such as fruits, vegetables, lean protein, and whole grains.

Avoid processed foods, sugary drinks, and high-fat foods.

A healthy diet can help promote weight loss and improve overall health when combined with metformin.

In terms of exercise, aim for at least 30 minutes of moderate-intensity exercise per day.

This can include activities such as brisk walking, jogging, cycling, or swimming.

Exercise helps to burn calories, build muscle, and boost metabolism, all of which can aid in weight loss.

Finally, getting enough rest is crucial for weight loss. Aim for 7–8 hours of sleep per night and avoid staying up late or using electronic devices before bed.

Lack of sleep can disrupt hormones that regulate appetite and metabolism, making it more difficult to lose weight.

Who Can Benefit from Metformin for Weight Loss?

Metformin may benefit individuals who are overweight or obese and have insulin resistance or type 2 diabetes.

It may also be helpful for individuals with polycystic ovary syndrome (PCOS), a condition that can cause weight gain and insulin resistance.

If you’re considering using metformin for weight loss, speaking with your doctor first is important.

They can help determine if metformin is right for you and what dosage to take. They can also monitor your progress and adjust your treatment plan as needed.

Precautions and Contraindications for Metformin Use

While metformin is generally considered safe, some precautions and contraindications should be considered. Metformin should not be used in individuals with:

  • Severe kidney disease
  • Liver disease
  • Heart failure
  • Alcoholism
  • A history of lactic acidosis

Metformin may also interact with other medications, so it’s important to tell your doctor about all your medications, including over-the-counter medications and supplements.

Conclusion and Outlook on Metformin Weight Loss

Metformin can be a helpful tool for weight loss, especially for individuals with insulin resistance or type 2 diabetes.

It reduces appetite, improves insulin sensitivity, and promotes weight loss.

However, combining metformin with healthy lifestyle changes such as a healthy diet, regular exercise, and adequate rest is important for maximum effectiveness.

If you’re considering using metformin for weight loss, speak with your doctor first.

They can help determine if metformin is right for you and what dosage to take. They can also monitor your progress and adjust your treatment plan as needed.

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Damin Lee
Change Your Mind Change Your Life

Evidence-based writer about health, weight loss, mindfulness, and more! My mission is to help you build healthy habits for success!