A Pap Smear for a Healthy New Year

Dr. Vedrana Högqvist Tabor
Clued In
Published in
5 min readJan 19, 2016

January is often a time for cleansing and dieting as a way to start off the new year healthy and fresh (Drynuary, anyone?). But if you’re not into detoxing, you can still kick off 2016 with something good for your health by taking advantage of Cervical Health Awareness Month. This January, the American Social Health Association (ASHA) and the National Cervical Cancer Coalition are raising awareness to encourage screening and HPV (human papillomavirus) vaccination.

If you don’t know what the cervix does or where it’s located, this is a good opportunity to get informed. The cervix is the lower, narrow end of the uterus that forms a canal between the uterus and vagina. It holds a key role in sex and reproduction, and its health is very important for maintenance of good overall health.

The most prominent disease affecting the cervix is cervical pre-cancer, in most cases chronic infection with high-risk human papillomavirus (HPV). Left untreated or detected late, these pre-cancers can progress to cervical cancer in 10 to 20 years.

Cervical cancer was once the most common cause of reproductive cancer death in the developed world. Today it has dropped to fourth place because of the availability of “secondary prevention methods” like screening, early diagnosis and treatment. Most cervical cancer deaths occur in low to middle income countries.

Most of the available tests are affordable, and they can detect pre-cancer. There are several affordable treatment options too. Even though a large portion of HPV infections (up to 90% within two years) as well as some pre-cancerous lesions do clear up, there is a risk that the infection can become chronic, and that precancerous lesions progress to cervical cancer.

Cervical cancer is highly curable if found early and treated. Routine screenings, which detect changes in cells lining the cervix, and treatment of these precancerous spots prevents almost half of all cervical cancers. Similar to most cancer cases, prognosis depends on how advanced the disease is at the time of diagnosis. The most important thing in preventing cervical cancer is yearly screening.

The good news is that over 90% of potential cervical cancers can be detected early by two tests:

  1. The Pap test (or Pap smear), which looks for changes in cervical cells. People between the ages of 21 and 65 should get a pap smear annually.
  2. The HPV test, which detects presence of the HPV virus.

HPV vaccines given to individuals before they become sexually active can prevent a large percentage of cervical cancer.

Signs and symptoms of early cervical cancer are usually not very noticeable, but may include the following:

(I) Vaginal bleeding

(II) Unusual vaginal discharge

(III) Pelvic pain

(IV) Difficult or painful sexual intercourse

(V) Postcoital bleeding

We highly recommend regular testing and annual checkups. If you experience any of the above symptoms, please visit and consult your doctor.

References

1. American Cancer Society: Cancer Facts and Figures 2015. Atlanta, Ga: American Cancer Society, 2015.

2. Ault KA: Epidemiology and natural history of human papillomavirus infections in the female genital tract. Infect Dis Obstet Gynecol 2006 (Suppl): 40470, 2006.

3. Brisson J, Morin C, Fortier M, et al.: Risk factors for cervical intraepithelial neoplasia: differences between low- and high-grade lesions. Am J Epidemiol 140 (8): 700–10, 1994.

4. Chen HC, Schiffman M, Lin CY, et al.: Persistence of type-specific human papillomavirus infection and increased long-term risk of cervical cancer. J Natl Cancer Inst 103 (18): 1387–96, 2011.

5. FDA Approves First Human Papillomavirus Test for Primary Cervical Cancer Screening [News]. Silver Spring, Md: Food and Drug Administration, 2014.

6. Ferlay J, Soerjomataram I, Ervik M, et al.: GLOBOCAN 2012 v1.0, Cancer Incidence and Mortality Worldwide. Lyon, France: International Agency for Research on Cancer, 2013. IARC CancerBase No. 11.

7. Herrero R, Hildesheim A, Bratti C, et al.: Population-based study of human papillomavirus infection and cervical neoplasia in rural Costa Rica. J Natl Cancer Inst 92 (6): 464–74, 2000.

8. Holowaty P, Miller AB, Rohan T, et al.: Natural history of dysplasia of the uterine cervix. J Natl Cancer Inst 91 (3): 252–8, 1999.

9. Khan MJ, Castle PE, Lorincz AT, et al.: The elevated 10-year risk of cervical precancer and cancer in women with human papillomavirus (HPV) type 16 or 18 and the possible utility of type-specific HPV testing in clinical practice. J Natl Cancer Inst 97 (14): 1072–9, 2005.

10. Muñoz N, Kjaer SK, Sigurdsson K, et al.: Impact of human papillomavirus (HPV)-6/11/16/18 vaccine on all HPV-associated genital diseases in young women. J Natl Cancer Inst 102 (5): 325–39, 2010.

11. Rodríguez AC, Schiffman M, Herrero R, et al.: Rapid clearance of human papillomavirus and implications for clinical focus on persistent infections. J Natl Cancer Inst 100 (7): 513–7, 2008.

12. Sasieni P, Castanon A, Cuzick J: Effectiveness of cervical screening with age: population based case-control study of prospectively recorded data. BMJ 339: b2968, 2009.

13. Sawaya GF, McConnell KJ, Kulasingam SL, et al.: Risk of cervical cancer associated with extending the interval between cervical-cancer screenings. N Engl J Med 349 (16): 1501–9, 2003.

14. Schiffman MH, Bauer HM, Hoover RN, et al.: Epidemiologic evidence showing that human papillomavirus infection causes most cervical intraepithelial neoplasia. J Natl Cancer Inst 85 (12): 958–64, 1993.

15. Schiffman M, Castle PE, Jeronimo J, et al.: Human papillomavirus and cervical cancer. Lancet 370 (9590): 890–907, 2007.

16. Schlecht NF, Kulaga S, Robitaille J, et al.: Persistent human papillomavirus infection as a predictor of cervical intraepithelial neoplasia. JAMA 286 (24): 3106–14, 2001.

17. The 1988 Bethesda System for reporting cervical/vaginal cytological diagnoses. National Cancer Institute Workshop. JAMA 262 (7): 931–4, 1989.

18. Trottier H, Franco EL: The epidemiology of genital human papillomavirus infection. Vaccine 24 (Suppl 1): S1–15, 2006.

19. Wright TC Jr, Massad LS, Dunton CJ, et al.: 2006 consensus guidelines for the management of women with abnormal cervical cancer screening tests. Am J Obstet Gynecol 197 (4): 346–55, 2007.

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Dr. Vedrana Högqvist Tabor
Clued In

CEO @Boost_HealthApp|| TEDx speaker || Cancer hunter || Hashimoto’s patient|| Parentpreneur || Learning from own mistakes since 1977