Vitamin D May Treat Covid-19, Suggests Bradykinin Hypothesis and New Clinical Results

Scientists say Vitamin D could emerge as one tool (among many others) for treating Covid-19 and its symptoms.

Thomas Smith
Covid-19 Bradykinin Hypothesis

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Photo by Ainsley Myles on Unsplash

Beginning in April of this year, a team at Oak Ridge National Laboratory used the powerful Summit supercomputer to analyze Covid-19. Their results became the basis of the bradykinin hypothesis, a new theory of how Covid-19 impacts the body which I covered in Elemental earlier this month.

One of the most surprising and compelling elements of the bradykinin hypothesis relates to Vitamin D. As the team described in their landmark, peer-reviewed paper in the journal eLife, “Vitamin D deficiencies have recently been associated with severity of illness in COVID-19 patients.” Based on the vitamin’s theorized role in promoting potentially deadly bradykinin storms in Covid-19 patients, the researchers found that “Vitamin D supplementation when warranted” could be a potential treatment for the disease.

The bradykinin hypothesis and its predictions were supported by gene expression, autopsy, and clinical data, but need further testing in clinical and laboratory settings. In their paper, the researchers clearly state that “the testing of any…pharmaceutical interventions should be…

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