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Toolbox Genomics Reviews: What You Should Know Before Buying

Toolbox Genomics Reviews: What You Should Know Before Buying

About Toolbox Genomics

Founded by Erika Gray and Elwina Hewitt in 2016, Toolbox Genomics provides alternative and holistic health services.

It is fundamentally a data interpretation service.

The company collects genetic data from its CLIA/CAP-certified labs to generate a personalized report with DNA and epigenetic insights.

Currently, Toolbox Genomics’ services are limited to the US only.

Toolbox Genomics Services

Both practitioners or general users can avail themselves of the company’s services.

The company offers two types of testing services.

DNA Test

The DNA test includes information on 16 health predisposition traits. It also has personalized advice about meal planning, fitness routines, and nutritional supplements.

Epigenetic Test

This test provides information on genes whose functions can be altered by environmental factors. The alterations can also be undone in some instances through targeted lifestyle interventions. This service is available for repeat testing to check whether a prescribed change has impacted the functioning of the gene or lack thereof.

Toolbox Genomics offers an app service, My Toolbox Genomics, available on the Apple App Store and Google Play.

Toolbox Genomics Report Review

Toolbox Genomics hosts its Practitioners exclusive products under three categories: For Licensed Practitioners and Wellness Professionals, For Licensed Practitioners, and the Key Opinion Leader Panels.

- For Licensed Practitioners and Wellness Professionals

Under this category, the company provides eight types of test panels:

- Epigenetics Panel is designed to help users understand the aging process.

Traits included

- Biological age
- Eye Age
- Hearing Age
- Memory Age
- Inflammation score

Image: Snippet from Toolbox genomics sample epigenetics report

- Respiratory Resilience includes genetic predispositions to conditions or nutrient deficiencies that may decrease respiratory resilience and increase viral susceptibility.

Traits included

- Vitamin D3
- Vitamin C
- Zinc
- Selenium
- Glutathione
- Vitamin A
- Inflammation
- Oxidative stress
- Blood pressure regulation
- Glucose metabolism
- COMT gene traits

Image: Snippet from Toolbox genomics sample Respiratory Resilience report

- Nutrition Optimization panel is designed to inform individuals about nutritional deficiencies, food intolerances, and metabolism.

Traits included

- Alcohol metabolism
- Caffeine metabolism
- Caffeine-related anxiety
- Calcium
- Choline
- CoQ10
- Folate
- Gluten sensitivity
- Iron
- Lactose intolerance
- Magnesium
- Omega-3
- Saturated fat response
- Selenium
- Vitamins A, B12, B6, C, and D3
- Zinc

Image: Snippet from Toolbox genomics sample nutrition report

Xcode Life’s Gene Nutrition Report — 48 Traits, $20 — No DNA test required

- Detox Panel contains insights into weight loss, skin irritation, mood irregularities, fatigue, and detoxification of toxins.

Traits/Genes included

- COMT
- CYP1A1
- CYP1A2
- CYP1B1
- CYP2s
- Estrogen metabolism
- Glutathione
- Inflammation
- MTHFR
- NAT
- Nrf2
- Oxidative stress
- SLC
- SOD
- SULT
- SUOX
- UGT

Image: Snippet from Toolbox genomics sample detox report

- Endurance Performance panel is designed exclusively for endurance athletes to help them improve their injury recovery and susceptibility, knowledge of muscle fiber types, and predisposed nutrition deficiencies.

Traits included

- Better endurance performance
- Injury risks like disc degeneration
- Ligament & tendon injury and muscle damage
- Iron
- Lactate
- Metabolic rate
- Motivation to exercise
- Muscle fiber type
- Novelty-seeking predisposition
- Obesity predisposition
- Recoveries including oxidative stress and sleep
- Response to endurance training
- VO2 max
- Weight & fat loss in response to exercise

Image: Snippet from Toolbox genomics sample endurance report

- Health Enrichment is a basic panel designed for someone new to genetic testing and includes information on almost everything like metabolism, nutritional deficiencies, workout suggestions & injury susceptibility.

Traits included

- Aging
- Blue light sensitivity
- Exercise & fat loss
- Heart health
- Lactose intolerance
- Motivation to exercise
- Obesity predisposition
- Sleep impairment
- Stress response
- Yo-yo dieting, etc.

Image: Snippet from Toolbox genomics sample health enrichment report

Xcode Life’s Gene Health Report — 55 Traits, $20 — No DNA test required

- Hormone panel covers aspects like hormone irregularities, depression, abnormal menstruation cycles, and libido.

Traits include

- Cortisol
- DHEA
- Estrogen
- Estrogen metabolism
- Progesterone
- Testosterone in men and women

Image: Snippet from Toolbox genomics sample hormone report

- Weight Management is curated for individuals who aim to maintain a healthy lifestyle and provides information on weight loss, predispositions to obesity & eating styles, and predisposition to processing different nutritional elements.

Traits include

- Dieting success
- Hunger
- Metabolic rate
- Obesity & artificially sweetened beverages
- Obesity predisposition
- Snacking
- Sweet tooth
- Weight-loss & low-fat diets
- Weight loss & protein diets
- Yo-yo dieting

Image: Snippet from Toolbox genomics sample weight management report

- For Licensed Practitioners

Toolbox Genomics offers 5 test panels exclusively for licensed practitioners.

- Cardiometabolic Panel analyzes 77 genes and covers traits like

- Coronary artery disease
- Diabetes
- Hypertension
- Inflammation
- Insulin resistance
- Lipid impairment with Lp(a)
- Metabolic syndrome
- Oxidative stress

Image: Snippet from Toolbox genomics sample cardiometabolic report

- Cognitive Panel analyzes 103 genes and covers

- Alzheimer’s disease
- Anxiety
- Concussion with TBI
- Dementia
- Depression
- Inflammation
- Mild cognitive impairment
- Omega-3
- Oxidative stress
- Parkinson’s disease

Image: Snippet from Toolbox genomics sample cognitive report

- Energy/Fatigue Panel analyzes 60 genes and covers traits, including

- Chronic fatigue syndrome
- Cortisol
- Depression
- Fibromyalgia
- Inflammation
- Migraines
- Musculoskeletal pain
- Osteoarthritis
- Oxidative stress
- Stress response

Image: Snippet from Toolbox genomics sample energy/fatigue report

- GI (Gastrointestinal) Panel analyzes 54 genes and covers

- Celiac disease
- Crohn’s disease
- Inflammation
- Irritable bowel syndrome (IBS)
- Ulcerative colitis traits

Image: Snippet from Toolbox genomics sample gastrointestinal report

- Immune Panel analyzes 98 genes and covers traits like

- Hashimoto’s thyroiditis
- Inflammation
- Multiple sclerosis
- Psoriasis
- Rheumatoid arthritis.

Image: Snippet from Toolbox genomics sample immune report

- Key Opinion Leader Panel

This test panel is an exclusive offering of Toolbox Genomics curated by Functional Medicine professionals renowned in their area of interest.

- Dr. Rob Gut/Brain Panel covers the analysis of 28 genes. It includes conditions like

- IBS
- Gluten sensitivity
- Lactose intolerance
- Celiac disease
- Inflammation
- Concussion with TBI

- Dr. Rob Musculoskeletal Panel analyzes 15 genes and covers traits like

- Musculoskeletal pain,
- Disc degeneration
- Muscle damage
- Vitamin D3
- Magnesium
- Vitamin C
- Muscle fiber type

Image: Snippet from Toolbox genomics sample musculoskeletal report

- Dr. Rob TBI/Concussion Panel analyzes 27 genes related to conditions like

- Inflammation
- Oxidative stress
- Mild cognitive decline
- Omega-3
- Concussion with TB

Image: Snippet from Toolbox genomics sample concussion report

Toolbox Genomics Products

For Practitioners

- HealthcarePro (HCP) Products

These products have been developed for licensed practitioners bearing an MD, NP, DO, DC, NMD, PA, PharmD, RN, and Dietitians. Such individuals can avail themselves of the HCP products (test ordering for their clients) by producing their licensure while mentioning their state of practice.

- WellnessPro (WPRO) Products

These products are offered to dietitians, health coaches, trainers, nutritionists, RNs, and other wellness professionals.

For Consumers

Clients can order either a DNA or epigenetics test (or both), which involves sending a saliva sample or cheek swab sample to the company.

DNA Test Package

This includes :

- Virus Risk Score (newly introduced)
- 16 Health Predisposition Traits
- Immunity

- Diet & Weight Loss
- Anti-Aging
- Mental Health & Memory
- Sleep
- Vitamin Deficiencies
- Stress
- Skin Health
- Supplement Response
- Injury Risk
- Muscle Health
- Eye Health
- Gut Health
- Heart Health
- Exercise Response
- Health Overview

- Custom Meal Plans
- Personalized Training Regimen
- Vitamin Recommendations

Epigenetics Test Package

This includes:

- Five insights to change, which provides for biological age, eye age, hearing age, memory age, inflammation score
- Tracking changes in DNA expression over time
- Impact of Air Quality on the client’s wellbeing curated by location

Consumers can also ask for only the DNA raw data files by writing at info@toolboxgenomics.com.

Getting Started with Toolbox Genomics

For Clients

- Purchase Toolbox Genomics Health Action Plan
- The company mails the DNA collection kit
- Account creation and signing of a consent form
- Register the kit using the barcode printed on the received kit.

Image: How to get started with Toolbox genomics

The DNA collection kit contains directions, a cheek swab, a DNA sample envelope, and a prepaid return envelope.

After successful registration, collect the sample and mail it to the company. Then, download the app and view the results.

Clients can expect their test results within six weeks. Although for an epigenetics test, results may take up to 6–8 weeks.

Pricing

TestPricingDNA Test$199Epigenetics Test$249DNA + Epigenetics Test$299

For more information, you can check out the pricing list.

About Toolbox Genomics Privacy

Toolbox Genomics claims protecting the client’s personal health information is among their top priorities and only helps guide their healthcare decisions. The company analyzes and interprets the client’s genetic data to curate personalized recommendations. The company claims to keep this genetic information “anonymized and de-identified” for privacy protection.

On registration, Toolbox Genomics collects the client’s name, DOB, email and shipping address, credit card information (for purchase purposes), ordering practitioner’s license type and number, and consent to share data with the client’s practitioner.

Additionally, upon registration, the company also asks for additional information in the form of a questionnaire which includes the client’s own and familial medical history, nutrition regimes, and diet. However, answering this questionnaire is optional.

The clients can opt for deactivation of their accounts by mailing the company at info@toolboxgenomics.com.

According to the company, data protection measures include:

- Data Security: Identifying data at rest is encrypted using either AES256 or AES128. Data in transit is encrypted using TLS to ensure your privacy.
- De-identified data and anonymity: All details used to identify you are separated from your genetic data. Our lab partners handle and process samples in a de-identified manner. This means all identifying information is separated from your genetic data.
- Website security: All web pages on toolboxgenomics.com are served over HTTPS.
- Personal Information: Your personal information is encrypted both when it’s at rest in our servers and when it’s in transit through the web.

For detailed information, please read the privacy policy.

News & Reviews

News

In June 2018, Toolbox Genomics partnered with the MedFit Education Foundation (MFEF) to educate fitness and healthcare professionals in translational genomics.

In Aug 2017, Toolbox Genomics made its app, My Toolbox Genomics, available in Sequencing.com’s app store.

Reviews

Innerbody reviews Toolbox Genomics as a company whose clients take tests primarily due to their healthcare practitioners’ recommendations.

dnatestingchoice.com ranks Toolbox Genomics as 4th in the Health Testing sector.

Summary: Pros & Cons

Pros

- Provides epigenetic insights in addition to DNA insights.
- Genetic testing focusing solely on health.
- Availability of personalized app service.

Cons

- Test pricing is expensive.
- Epigenetic test results take a lot of time (6–8 weeks).
- Practitioner involvement is required to sign up for tests.
- Global service is not available.
- Tricky test order service.

Toolbox GenomicsXcode LifeType of genetic testingDNA kitDNA raw data analysisAncestry reportsNot offeredNot offeredHealth reportOfferedOfferedPharmacogenomic reportNot offeredOfferedRaw data uploadUnavailableDNA raw data from all major providers accepted. Comprehensive listNumber of traits analyzed150+700+Report updatesNoYesPriceDNA test: $199Epigenetic test: $249DNA + Epigenetic test: $299Reports: $10-$40Bundles: $49-$99Price detailsFree toolsUnavailable3 free tools (Gene Tool, DNA raw data merge, DNA raw data convert) available for allSample reportsAvailable as PDFAvailable as detailed report walkthrough videos

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