Why alcohol poses a greater danger to women

Being a social woman, I frequently find myself having an extra glass of wine just to align with the group’s mood. However, this norm poses a greater health risk for women compared to men.

Maria Kovalevich
GentleBlog
Published in
7 min readNov 19, 2023

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a purple glass in front of white bottles
Illustration by Maria Kovalevich

A lot of research, which you can find at the end of this article, shows that alcohol has a bigger effect on women than on men.

This is not just because of how our bodies are different, but also because of what society expects from us.

Biological vulnerabilities

It’s well-known that men and women’s bodies are built differently. But how do these differences amplify the risks of alcohol for women?

Let’s explore:

1. Body composition differences

Women’s bodies typically have a higher fat content and less water compared to men’s. Why does this matter? Alcohol is soluble in water, not fat. So, in women, alcohol remains more concentrated and less diluted, leading to higher and more prolonged alcohol levels in the bloodstream. This biological fact makes women more vulnerable to alcohol’s effects.

2. Enzymatic differences in alcohol metabolism

Also, women have less of two important enzymes — alcohol dehydrogenase and aldehyde dehydrogenase — that help break down alcohol in the stomach and liver. Because of this difference in enzymes, more alcohol goes into the bloodstream, making its effects on the body stronger.

The video below illustrates how alcohol is metabolised differently in the bodies of women and men. For women, alcohol (or ethanol, shown as green dots) is minimally processed and travels quickly from the stomach to the liver and then into the bloodstream. In contrast, men have a higher activity of the alcohol dehydrogenase enzyme in the stomach, converting ethanol more efficiently into acetaldehyde (shown as red dots). This results in a lower amount of alcohol entering the male bloodstream compared to females when consuming an equal volume of alcohol.

Male versus female alcohol metabolism: Males break down alcohol faster, leading to lower blood alcohol concentrations than females for the same alcohol amount. Video from Pharmacology Education Partnership.

3. Impact of hormonal fluctuations

The menstrual cycle brings about fluctuating hormone levels, like oestrogen and progesterone, which can alter alcohol metabolism. For example, when oestrogen levels are high, alcohol is processed faster, leading to quicker intoxication. This hormonal rollercoaster adds another layer to how women metabolise alcohol differently.

4. Increased risk of alcohol-related health issues

Due to these biological differences, women face a heightened risk of various health issues related to alcohol use. These can include liver damage, heart disease, and brain damage, which may develop more quickly and from lower levels of alcohol consumption compared to men.

Societal pressures and stigma

a cartoon of a girl with a sad face
Illustration by Maria Kovalevich

The challenge women face with alcohol doesn’t just stop at biology; it’s also woven into societal attitudes. Here’s the paradox: women are often held to a stricter standard when it comes to alcohol addiction compared to men. Yet, at the same time, they’re expected to keep up in social settings where drinking is the norm.

This creates a hidden struggle. Imagine the pressure to drink just to blend in, all the while dealing with the harsh judgment specifically reserved for women who drink. It’s a silent battle, with societal norms pushing women to drink and stigmas punishing them for it.

Enter the pandemic, and this scenario gets even more complex. The RAND Corporation conducted a study that revealed a stark increase in heavy drinking among women during these times. Why? The overwhelming stress and anxiety brought on by COVID-19 pushed many towards alcohol as a coping mechanism. The result? An unfortunate spike in health risks, adding another layer to the already challenging relationship between women and alcohol.

How much alcohol is actually safe?

wine glasses
Illustration by Maria Kovalevich

After diving into numerous studies, it’s tough to find a straightforward answer. So, let’s look at this in two parts:

1. Research speaks in favor of one drink a day:

Several research pieces and guidelines suggest that sticking to one alcoholic drink per day is a wise move. For women, this is the norm, and recent shifts in guidelines are now suggesting the same for men.

What’s a “drink”, anyway? Think about one can of beer, a glass of wine, or a shot of liquor.

A global study, as reported by AP News, echoes this “one drink a day” rule, pointing out that many countries’ guidelines might be too relaxed.

The 2020–2025 Dietary Guidelines for Americans also back this up, advising adults to opt for moderation — one drink or less per day for women and two or less for men.

a can of beer, a glass of wine, a shot of liquor.
Illustration by Maria Kovalevich

2. Studies warning against any alcohol:

It’s crucial to consider research indicating that any alcohol can be harmful, especially for those in middle age.

Time.com covered a study showing there’s no safe level of alcohol use.

Harvard T.H. Chan School of Public Health’s research also flags even moderate drinking as harmful.

Other studies in 2018 and 2023 link alcohol to health risks, including higher blood pressure and increased cancer risk, even at low consumption levels.

This suggests a need to rethink alcohol guidelines, particularly for middle-aged individuals.

In summary: choosing to drink is personal. But remember, factors like weight, overall health, genetics, family history, your last meal, age, and gender all play a role in how alcohol affects you. It’s not just about the drink count.

Steps to support women’s health in the context of alcohol

a black flower in a vase
Illustration by Maria Kovalevich

Acknowledging and understanding the unique challenges women face with alcohol is key to making a positive change. Here’s how we can create a more supportive environment:

  1. Raising awareness: healthcare providers, policymakers, and society need to recognise the specific risks alcohol poses to women. It’s not just about general awareness, but about creating a space where women are empowered to make well-informed decisions about their health.
  2. Educational programs: these should focus on the gender-specific risks of alcohol, particularly how it affects women’s liver health. By shining a light on these specific risks, we can help women understand and navigate their unique vulnerabilities.
  3. Training healthcare providers: medical professionals should receive training to proactively identify and address alcohol use in women. It’s about moving beyond the basics and equipping them with the knowledge and tools to effectively support women in this area.
  4. Customised support systems: support shouldn’t be one-size-fits-all. It needs to be tailored to meet the specific needs of women, recognizing that their experiences and challenges with alcohol can be quite different from men’s.

By taking these steps, we can move towards a future where women’s health concerns, particularly regarding alcohol, are not just recognised but actively addressed through informed and empathetic care.

A healthier road ahead for women

Understanding how alcohol affects women differently is key.

It’s a complicated issue that really needs everyone — from doctors to lawmakers to all of us in society — to work together.

What we need to do is bring these issues into the open, talk about them, and make sure that the way we handle alcohol is really looking out for women’s unique needs.

By focusing on this, we can start to make a real difference. We’re not just trying to raise awareness here — we’re aiming to change things for the better.

The end goal? A world where women’s health issues, especially those related to alcohol, aren’t hidden away but are known, talked about, and taken care of properly.

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Maria Kovalevich
GentleBlog

Product designer exploring human-centered product development through affective computing. Working on begentle.app