Glycans — predictive biomarkers of cardiometabolic risk

Ana Cvetko
GlycanAge Science
Published in
2 min readJan 29, 2020

In the scientific community one of the best measures of article’s impact is how ‘’popular’’ the article is, meaning how much the scientists and researches talk about it. One of the most ‘’popular, talked-about’’ recently published article (measured by Altmetric) is centered around the importance of our fascinating glycans, this time as predictors of cardiometabolic risk.

In this article, the authors first introduce us to the growing problem that cardiometabolic diseases are, stating that they are a major public health burden. Different medical conditions are considered a cardiometabolic disease, like type 2 diabetes, stroke or heart attack. Prevention of these serious health issues could definitely improve general public health but also decrease the burden of the vast therapies issued for these patients.

The authors assessed the predictive value of glycans alone and of glycans combined with known risk predictors for cardiometabolic diseases.

Firstly, they examined the prediction of type 2 diabetes. The statistical analysis showed glycans to be highly predictive for type 2 diabetes as a stand-alone prediction biomarker. Furthermore, they showed that combining glycans with a known type 2 diabetes risk prediction tool called German Diabetes Risk Score, GDRS, improved the prediction of type 2 diabetes.

Secondly, they explored the same for cardiovascular diseases. This time glycans were mildly predictive, but again improved prediction when they were merged with the AHA score, a known cardiovascular risk prediction tool of the American Heart Association.

I’ve mentioned multiple times that GlycanAge is the best biomarker of your biological age because glycans reflect your overall health which changes accordingly to your lifestyle habits and medical conditions. People usually focus more on lifestyle habits because unhealthy diet, non-exercising, not sleeping enough or smoking will show their effect on your skin, nails and overall appearance sooner than underlying unknown medical conditions. But these conditions can lead to serious consequences and can be worsened by bad habits. This article confirms that your GlycanAge can tell you if something serious is happening with your organism even if you haven’t noticed the symptoms yet. With GlycanAge you can finally have a complete picture of your health and find out what’s happening both on the inside and outside.

Find out your biological age using our GlycanAge test. It’s never too early to start taking a closer look at your health.

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