Health and Disease

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Cancers cells have mitochondrial DNA missing

Cancers cells have mitochondrial DNA missing

Next-generation DNA sequencing data reveals that many tumour cells have depleted levels of mitochondrial DNA.

eLife1 hr ago

Flawed animal experiments might have overestimated one drug’s effects by 45%

Flawed animal experiments might have overestimated one drug’s effects by 45%

Report claims that poor study design threatens the validity of preclinical research into the anti-cancer drug sunitinib.

eLifeOct 19, 2015

Tightening the net on malaria

Tightening the net on malaria

Africa needs more insecticide-treated nets to combat malaria, and better systems to make sure the extra nets are sent where they are most…

eLifeApr 4

Flu viruses join forces

Flu viruses join forces

Two influenza viruses infect more cells when they cooperate.

eLifeMar 20

Bacterial pathogens exploit a hidden path

Bacterial pathogens exploit a hidden path

Direct contact between host cells allows some bacteria to spread without being attacked by the immune system.

eLifeMar 7

Why does Down syndrome cause heart defects?

Why does Down syndrome cause heart defects?

Researchers have used mouse models to ask which genes cause the heart defects often seen in Down syndrome.

eLifeFeb 29

Mouse model shows new target for TB vaccine

Mouse model shows new target for TB vaccine

New research highlights the potential of using mycolic acids to generate an effective vaccine against tuberculosis.

eLifeFeb 21

Cancer cells ignore “stop signs”

Cancer cells ignore “stop signs”

Kidney cancer cells often ignore the stop signs at the end of genes, and thus make unusual gene products that might promote the development…

eLifeFeb 16

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