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My Comprehensive Guide to Diabetes Medications

Understanding the Medications I Use to Manage My Diabetes

Bob Cliffhanger
Published in
3 min readJul 29, 2024

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The people who think Diabetes is an incurable disease, then you are thinking wrong. Managing diabetes involves more than just diet and exercise; but you have to know that the medications also play a crucial role. Over the years, I’ve become familiar with various diabetes medications and how they help control my blood sugar levels. Here is my comprehensive guide to the medications I use to manage my diabetes effectively, without insulin.

1. Metformin
What It Does: Metformin helps lower blood sugar by reducing glucose production in the liver and improving insulin sensitivity.
My Experience: Metformin was one of the first medications I was prescribed. It’s been effective in helping me maintain stable blood sugar levels with minimal side effects.
2. Sulfonylureas
Examples: Glipizide, Glyburide
What They Do: These medications stimulate the pancreas to release more insulin.
My Experience: I’ve used sulfonylureas ( Glipizide) to boost my insulin production, especially when my blood sugar levels were harder to control.

The Following were experienced by my Dad and some of my relatives:
3. DPP-4 Inhibitors
Examples: Sitagliptin (Januvia), Saxagliptin (Onglyza)
What They Do: DPP-4 inhibitors help increase insulin release and decrease glucose production by enhancing the action of incretin hormones.

Experienced by one of my Relatives: These have been helpful in managing his blood sugar without causing significant weight gain or hypoglycemia.
4. GLP-1 Receptor Agonists
Examples: Exenatide (Byetta), Liraglutide (Victoza)
What They Do: These medications mimic the incretin hormone GLP-1, which increases insulin release and decreases appetite.
Experienced by one of my Relatives: GLP-1 receptor agonists controlled his appetite and helped him in weight management alongside blood sugar control.
5. SGLT2 Inhibitors
Examples: Canagliflozin (Invokana), Empagliflozin (Jardiance)
What They Do: SGLT2 inhibitors work by preventing the kidneys from reabsorbing glucose, which is then excreted in urine.
Experienced by one of my Relatives: These medications have helped reduce her blood sugar levels and have the added benefit of lowering blood pressure.
6. Meglitinides
Examples: Repaglinide (Prandin), Nateglinide (Starlix)
What They Do: Meglitinides stimulate the pancreas to release insulin in response to a meal.
My Dad’s Experience: These medications helped for controlling blood sugar spikes after meals, offering more flexibility in my dad’s diet.
7. Thiazolidinediones
Examples: Pioglitazone (Actos), Rosiglitazone (Avandia)
What They Do: Thiazolidinediones help increase insulin sensitivity in fat and muscle tissues.
Experienced by one of my Relatives: While effective, he’ve been cautious with these due to potential side effects like weight gain and fluid retention.
8. Alpha-Glucosidase Inhibitors
Examples: Acarbose (Precose), Miglitol (Glyset)
What They Do: These medications slow the breakdown of carbohydrates in the intestines, which helps prevent blood sugar spikes.
My Dad’s Experience: They’ve been useful for managing post-meal blood sugar levels, though they require careful meal planning.

Conclusion

Overall, Understanding medications played a crucial role in managing my diabetes. Each type has its role, and finding the right combination has been a process of trial and error with my healthcare team. By staying informed and proactive, I can better control my diabetes and maintain a healthier lifestyle.

Ps: Manage your diabetes with consultation of your doctor for medications.

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Bob Cliffhanger
Health and  Science

Bob Cliffhanger crafts thrillers with twists that leave readers breathless. Follow for more on the art of suspense.