Where do the complications come from

Have you ever wondered why there’s so much work in science? Why don’t we get the things done so quickly and neatly as we’d expect from those highly educated and motivated messieurs and mesdames? It’s a lot of work and sometimes scientists don’t have a clue where you think they have — that’s why. To obtain this nice pic of mice hippocampus cell one must 1) get a cell culture (from an alive creature), 2) keep it alive, 3) either insert a dye to the cell or reprogram the mice DNA in advance to make the cells glow because of GFP (green fluorescent protein), 4) eventually, the pic itself is not of much interest, you’d possibly like to measure something from it. To measure the neurotransmitter or voltage induced ion flows in a cell (that’s how the signals in your brain transmit), you need to do a lot of sophisticated electrophysiology stuff that is a target of investigation in its turn. The method for neuronal ion fluxes measurement was discovered only in the late 1970s and the Nobel prize for it was obtained in 1991. Every step here is the object of intense research. People still get Nobel prizes for very, very simple ideas and one-line equations. Though I’m not a biologist, just an occasion to post the cell after participation in the process

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