Emerging Concerns of Elevated Uric Acid on Obesity, Diabetes, Heart Disease, Impotence, & Dementia
Hyperuricemia is increasing globally and affecting millions of Americans. Why does the body create excessive uric acid, and how can we lower its impact to prevent associated disorders?
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Understanding the adverse effects of waste products, which we call cellular debris, on the brain has been a strong research interest for me. Cellular debris mainly comprises damaged organelles, misfolded proteins, and some degraded neurotransmitters.
However, during my research into metabolism in the 1990s, I also encountered waste products the cells, tissues, and organs create due to the metabolic processes. In the early 2000s, several studies indicated that elevated uric acid was a predictor of cardiovascular mortality.
For example, I came across an eye-opening investigation paper published in JAMA in 2004 titled Uric Acid Level as a Risk Factor for Cardiovascular and All-Cause Mortality in Middle-aged Men. These researchers concluded that serum uric acid levels are a strong predictor of cardiovascular disease…
