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Litmus Health
The Litmus Papers
Published in
2 min readApr 3, 2024

The clinical trials landscape is undergoing a quickly-devloping and profound transformation driven by cutting-edge digital technologies and data-driven approaches. From leveraging wearables to capture rich real-world data to addressing the barriers to diverse participant enrollment in decentralized trials, here’s a little collection of some of the most important innovations reshaping how clinical research is conducted.

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MedTech Innovations, March 4th, 2024

Wearable technology holds immense potential to revolutionize clinical research by providing richer, more comprehensive real-world data, thereby augmenting trial efficiency and fostering superior patient outcomes. This approach offers advantages, including enhanced patient-centricity through reduced site visits, proactive health management via early detection of adverse events, diverse data types beyond standard clinical metrics, and the mitigation of missing data through improved adherence.

Applied Clinical Trials, March 11th, 2024

The advent of decentralized clinical trials (DCTs) raised hopes of increasing representativeness through alleviating geographic and logistical barriers to participation, but significant hurdles remain. A fundamental impediment is the lack of connectivity, as many underrepresented populations reside in areas with limited or no broadband internet access required for DCTs. Rigorous measurement elucidating the real-world effects of decentralization on representative enrollment is crucial for widespread endorsement of this methodology to enhance inclusiveness in clinical research.

Clinical Leader, March 12th, 2024

Real-world data (RWD), encompassing patient health status and healthcare delivery information routinely collected from sources such as electronic health records, claims, registries, and personal devices, offers multifaceted benefits for enhancing clinical trials. RWD can facilitate patient recruitment by efficiently identifying eligible participants through database analysis, while informing study design and protocol development by providing insights into disease epidemiology, clinical practices, and population characteristics.

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Podcast: Medical Design Briefs, April 3rd, 2024

On this episode of Medical Design Briefs, Rob Batchelor, head of biosensors at Nutromics explores the latest developments in aptamer-based biosensors, discussing how they enable real-time monitoring of vital signs, biomarkers, and health parameters.

Video: The Medicine Maker, March 12, 2024

In the wake of the COVID-19 pandemic, clinical researchers were driven to sourcing and enrolling trial participants in new ways, which has enabled more diverse demographics to participate. With the expanded representation of cultural minorities, our experts expect more accuracy in the growing data sets, but what other advantages are there to decentralized clinical trials?

In this video roundtable, Lokavant CEO Rohit Nambisan, Medable CSO Pam Tenaerts, and Curavit Clinical Research CEO Joel Morse discuss the increasing use of digital technology in decentralized clinical trials.

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Litmus Health
The Litmus Papers

Litmus is a clinical data science platform focused on health-related quality of life.