Hypothetical Lasting Health Problems of mRNA Vaccine vs. Coronavirus

Which risk would you take?

Shin Jie Yong, MSc (Res)
Microbial Instincts

--

Medical vector created by GarryKillian — www.freepik.com

Although the current vaccines for Covid-19 — Pfizer-BioNTech and Moderna mRNA vaccines —have over 90% efficacy rate, they have no long-term medical history. So nobody knows if mRNA vaccines would pose any harm in the long-run. But we also don’t know the same about the novel coronavirus — SARS-CoV-2 — that causes Covid-19. So, let’s see what are the hypothetical possibilities for each scenario.

mRNA vaccine

1. Messenger RNA (mRNA)

Truly an innovative vaccine strategy, mRNA vaccines are easier to make compared to traditional vaccines. It also has a higher efficacy as mRNA vaccines make the host cells produce the protein, which is more stable than traditional vaccines that introduce the protein into the body.

But mRNA vaccines are new, lacking a long-term safety profile. Currently, clinical trials only have safety data for at least two months.

One argument supporting the long-term safety of mRNA vaccines is that mRNA genetic material is incredibly fragile, to the point where such vaccines have a strict storage condition at -20 to -80°C coldness. At least in animal experiments, the mRNA in mRNA vaccines got degraded within 48 hours. As…

--

--

Shin Jie Yong, MSc (Res)
Microbial Instincts

Independent science writer and researcher | Named Standford's world top 1% scientists | Medium's boost nominator | Elite Powerlifter | Ghostwriter | Malaysian