Probing Evolution

Many Strains of Coronavirus Are Out There, but Only One Is Important

Scientists analyzed functions of over 100 distinct SARS-CoV-2 variants — how many strains did they find?

Shin Jie Yong, MSc (Res)
Microbial Instincts
6 min readAug 24, 2020

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Image by rawpixel.com

A study published July in the Frontiers of Microbiology, titled “Geographic and Genomic Distribution of SARS-CoV-2 Mutations,” conducted the largest bioinformatics analysis to date. From a total of 48,635 genomes of SARS-CoV-2 isolated from laboratories across the world, the study identified 353,341 mutational events. “Our analysis…confirms a low mutation rate of the virus, with an average of 7.23 mutations per sample with respect to the reference SARS-CoV-2 genome sequences,” the authors remarked.

The most prevailing mutation in this study is D614G, where the amino acid at position 614 changed from D (aspartic acid) to G (glycine); the prior D614 now becomes the G614 variant. Other studies agree that G614 is the dominant variant that represents 75.7% of all circulating SARS-CoV-2 worldwide as of July. For more information about what the D614G mutation means for the pandemic, kindly see here:

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Microbial Instincts
Microbial Instincts

Published in Microbial Instincts

Decoding the microbial angle to health and microbial world (under Medium Boost program).

Shin Jie Yong, MSc (Res)
Shin Jie Yong, MSc (Res)

Written by Shin Jie Yong, MSc (Res)

Named Standford's world top 1% scientists | Medium's boost nominator | National athlete | Ghostwriter | Get my Substack: https://theinfectedneuron.substack.com/