Why Covid Long-Haulers Should Be Careful About Vaccines

Understanding who might be at risk for post-vaccine autoimmunity, including mRNA-based vaccines.

Shin Jie Yong, MSc (Res)
Microbial Instincts

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In 2011, Yehuda Shoenfeld, MD, a world-leading autoimmunity professor with over 1,700 peer-reviewed publications, coined the term ASIA: Autoimmune/inflammatory Syndrome Induced by Adjuvants. It’s also called Shoenfeld’s syndrome or post-vaccination autoimmunity. Here comes a predicament: Should people at risk for ASIA, such as those with autoimmune conditions like Covid-19 long-haulers, get a vaccine?

A backdrop on ASIA

Adjuvant, the second A in ASIA, means to aid in Latin. In medicine, an adjuvant is a substance that boosts immune responses to a vaccine. Common adjuvants include alum, squalene, killed bacterial products, and mineral oil. Adjuvants can also be found elsewhere, such as silicone breast implants or cosmetic fillers.

While the biomolecular mechanisms of ASIA are complex and variable, the simple reason is that the immune system of some may be frailer to stimulation than others, leading to more chaotic immune responses.

Evidently, persons with these traits are already prone to autoimmune diseases, and the adjuvant in…

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Shin Jie Yong, MSc (Res)
Microbial Instincts

Independent science writer and researcher | Named Standford's world top 1% scientists | Medium's boost nominator | Elite Powerlifter | Ghostwriter | Malaysian