A Stealthy Harvard Startup Wants to Reverse Aging in Dogs, and Humans Could Be Next

Biologist George Church says the idea is to live to 130 in the body of a 22-year-old

MIT Technology Review
MIT Technology Review

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Photo: Matt Cardy/Getty Images

By Antonio Regalado

The world’s most influential synthetic biologist is behind a new company that plans to rejuvenate dogs using gene therapy. If it works, he plans to try the same approach in people, and he might be one of the first volunteers.

The stealth startup Rejuvenate Bio, cofounded by George Church of Harvard Medical School, thinks dogs aren’t just man’s best friend but also the best way to bring age-defeating treatments to market.

The company, which has carried out preliminary tests on beagles, claims it will make animals “younger” by adding new DNA instructions to their bodies.

Its age-reversal plans build on tantalizing clues seen in simple organisms like worms and flies. Tweaking their genes can increase their life spans by double or better. Other research has shown that giving old mice blood transfusions from young ones can restore some biomarkers to youthful levels.

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MIT Technology Review
MIT Technology Review

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