5 most important considerations for biological data analysis

Ignoring these fundamentals could lead to wrong interpretation of data that complicates your machine learning models

Kuan Rong Chan, Ph.D.
Omics Diary

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It’s a great sense of achievement to know that you have finished analysing your dataset. However, it is almost always a good habit to check through your data analysis and at times, even re-analyse the data in a different way to understand the data better and make the data analysis more outstanding. In this blog entry, I will highlight some key considerations that could be taken into account when checking through your data analysis.

  1. Could your variables be categorised differently, or expressed as continuous variables for data analysis?
Two different ways of showing association of age with antibody responses

In some instances, the explanatory variable can be expressed as a categorical variable or a continuous variable. If that is indeed the case, I would recommend analysing the data both ways. For example, consider a research question that studies the effect of age on vaccine antibody response. Based on literature, you may have classified subjects into two groups: (I) elderly subjects as 65 years of age and above; (II) young subjects as lower than 65 years of age. The antibody responses are then compared in these 2 groups.

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Kuan Rong Chan, Ph.D.
Omics Diary

Kuan Rong Chan, PhD, Senior Principal Research Scientist in Duke-NUS Medical School. Virologist | Data Scientist | Loves mahjong | Website: kuanrongchan.com