Cleaning Up Cells as Potential Treatment for Alzheimer’s Disease

A study in mice suggests that supporting autophagy in brain cells could ameliorate symptoms of Alzheimer’s disease

Gunnar De Winter
Predict

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(Pixabay, geralt)

The rise of the elderly

Modern medicine and healthcare have caused average life expectancy to rise. As a result, the elderly (>65 years of age) are the most rapidly growing demographic group globally.

One of the worries about this coming ‘gray tide’ is that it could prove to be a substantial healthcare burden, not in the least due to Alzheimer’s disease and other forms of dementia.

Alzheimer’s disease is a progressive brain condition associated with cognitive, memory, and behavioral problems. Several genes are involved in Alzheimer’s disease, with APOE being a major one. A specific version of this gene, APOEε4, is associated with a significantly increased risk for Alzheimer’s.

But genes are not (entirely) destiny. Lifestyle factors influence the risk for developing Alzheimer’s regardless of your genetic predisposition. Exercise— both mental and physical — reduces the risk. Physical exercise is good for your brain, as is mental exercise. Reading, writing, playing games, learning a new language, making music… All these activities

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