Prostate Cancer: Introduction

JAG
Radonc
Published in
1 min readNov 11, 2016

Epidemiology

  • USA: 240K diagnosed per yea
  • USA: 30K die of prostate cancer

Prognosis

  • Patients who undergo definitive treatment with a radical prostatectomy typically are quoted 5 and 10 year biochemical progression free survival (PFS) rates of 80% and 68%, respectively.
  • Radiotherapy, consisting of either external beam radiation therapy or brachytherapy, can also be utilized for definitive therapy of clinically localized prostate cancer, with a 10-year biochemical PFS of 50 — 70%.
  • Despite high cure rates with definitive therapy, approximately 35% of patients will still experience a biochemical recurrence within 10 years of receiving treatment. Among patients who develop biochemical recurrence, approximately one-third will develop radiographic evidence of metastatic disease within 8 years from the time of PSA elevation.

Among patients who develop biochemical recurrence, approximately one-third will develop radiographic evidence of metastatic disease within 8 years from the time of PSA elevation.

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