Brain Cancer News Update

Latest Headlines in 2018

Randy’s Club is dedicated to the advancement of research and education that will improve individuals quality of life. Started in memory of Randy Strause, father and husband, who died of brain cancer, we pride ourselves on keeping up with research, from pre-clinical animal and cell models to clinical trials in humans. Given the recent attention to glioblastoma, an incurable brain cancer, we wanted to share with our readers what is happening this year.

  1. Brain Cancer Potentially Resists Immunotherapies by Trapping T Cells in Bone Marrow Aug. 20, 2018 — Researchers have found that brain tumors in mice and humans cause immune T-cells to become trapped in bone marrow. This ... read more
  2. Scientists Discover Chemical Which Can Kill Glioblastoma Cells Aug. 15, 2018 — Aggressive brain tumor cells taken from patients self-destructed after being exposed to a chemical in laboratory tests, researchers have ... read more
  3. Missing Immune Cells That Could Fight Lethal Brain Tumors Aug. 13, 2018 — Researchers have tracked the missing T-cells in glioblastoma patients. They found them in abundance in the bone marrow, locked away and unable to function because of a ... read more
  4. Origin Cells for Deadly Brain Tumors Identified Aug. 2, 2018 — A new study identified where the mutation causing glioblastoma starts. According to the study, neural stem cells away from the tumor mass are the cells of origin that contain ... read more
  5. Magnetic Nanoparticles Deliver Chemotherapy to Difficult-to-Reach Spinal Tumors July 30, 2018 — Researchers have demonstrated that magnetic nanoparticles can be used to ferry chemotherapy drugs into the spinal cord to treat hard-to-reach spinal ... read more
  6. Leopard Geckos Can Make New Brain Cells July 28, 2018 — Researchers have discovered the type of stem cell allowing geckos to create new brain cells. This finding provides evidence that lizards may also be able to regenerate parts ... read more
  7. Altitude Sickness Drug Appears to Slow Progression of Glioblastoma July 9, 2018 — A drug used to treat altitude sickness may help patients with glioblastoma, according to a new ... read more
  8. A First Look at Interstitial Fluid Flow in the Brain July 3, 2018 — Past research has shown a link between interstitial fluid flow and an increased invasion rate of glioblastoma cells, and biomedical researchers and electrical engineers recently developed a new ... read more
  9. Men and Women Have Different Genetic Risk Factors for Developing Brain Cancer June 28, 2018 — Researchers have discovered that men and women have different genetic risk factors for developing ... read more
  10. Poliovirus Therapy for Recurrent Glioblastoma Has Three Year Survival Rate of 21 Percent June 26, 2018 — A genetically modified poliovirus therapy developed at Duke Cancer Institute shows significantly improved long-term survival for patients with ... read more
  11. Researchers Clarify Role of Mutations in Glioblastoma July 11, 2018 — Researchers investigated whether the location of the mutation within the sequence of the PIK3CA gene affected the mutation's ability to help drive growth of glioblastoma tumors. They also ... read more
  12. Brain Metastases Common and Difficult to Treat in ROS1 Lung Cancer July 10, 2018 — Brain metastases were found to be fairly common in stage IV ROS1-positive cancers and in 47 percent of ROS1 patients, the brain was the first and only site of ... read more
  13. Reviving the Protector: New Tactic Against Medulloblastoma June 11, 2018 — Scientists have a new tactic with potential for fighting medulloblastoma, the most common and most aggressive form of brain tumor in ... read more
  14. New Combination Treatment Against Relapsed Head and Neck Cancer June 6, 2018 — The five-year survival rate for locally-advanced head and neck cancer is only 46 percent, even with treatments including surgery, radiation, chemotherapy and/or genetically targeted treatments such ... read more
  15. Experts and AI Help Glioblastoma Research and Treatment Efforts June 6, 2018 — It takes an 'A' team to make headway against glioblastoma, a highly aggressive type of brain cancer. Glioblastoma is the most common type of malignant brain tumor in adults. In addition to ... read more
  16. Personalized Cancer Vaccine May Increase Long-Term Survival in Patients With Deadly Brain Cancer June 4, 2018 — A new study has found that a personalized glioblastoma vaccine may increase long-term survival in some patients. Nearly 30 percent of patients in the current trial have now survived at least three ... read more
  17. Virtual Brain Could Aid Surgical Planning May 29, 2018 — Researchers have simulated neural activity based on the unique structural architecture of individual brain tumor patients using a platform called The Virtual Brain. The findings are a first step ... read more
  18. MR Spectroscopy Imaging Reveals Effects of Targeted Treatment of Mutant IDH1 Gliomas May 18, 2018 — Using a novel imaging method, a research team is investigating the mechanisms behind a potential targeted treatment for a subtype of the deadly brains tumors called ... read more
  19. Gadolinium Deposition in the Brain Not Dose Dependent May 11, 2018 — Investigators have determined that in children receiving gadolinium as a contrast agent to enhance MRI examinations, signal changes attributed solely to deposition of this material in the brain are ... read more
  20. Operating on Brain Gliomas by Detecting the 'Glow' May 9, 2018 — Scientists report on novel imaging technology for malignant brain ... read more
  21. Gliomas: Persistence Pays Off in Discovery That Could Lead to Improved Treatment and Survivability of Patient May 1, 2018 — Gliomas are the most common type of central nervous system cancer but how these tumors develop is not fully understood. Sheri Holmen, PhD a researcher at Huntsman Cancer Institute (HCI) and professor ... read more
  22. Noninvasive Brain Tumor Biopsy on the Horizon Apr. 26, 2018 — Taking a biopsy of a brain tumor is a complicated and invasive surgical process, but a team of researchers is developing a way that allows them to detect tumor biomarkers through a simple blood ... read more
  23. Organoids Reveal How a Deadly Brain Cancer Grows Apr. 24, 2018 — Scientists developed a new model for glioblastoma using gene-edited ... read more
  24. The Role of 'Extra' DNA in Cancer Evolution and Therapy Resistance Apr. 23, 2018 — Researchers tracked genomic alterations detected in patient samples during tumor cell evolution in culture, in patient-derived xenograft (PDX) mouse models from the cultures, as well as before and ... read more
  25. Possible Novel Method for Stopping Untreatable Pediatric Brain Cancers Apr. 17, 2018 — Researchers used an experimental molecular therapy in preclinical laboratory tests to effectively treat several types of deadly pediatric brain cancer and now propose advancing the treatment to ... read more
  26. Altered Immune Cells Clear Childhood Brain Tumor in Mice Apr. 16, 2018 — In mice, a fatal brainstem tumor was cleared by injecting it with engineered T cells that recognized the cancer and targeted it for destruction. The discovery is moving to human ... read more
  27. Launch Switch for Most Common Malignant Pediatric Brain Tumor Mar. 29, 2018 — A delicate balance during brain development could have profound implications for understanding and treating medulloblastoma, the most common malignant brain tumor affecting ... read more
  28. Metastatic Lymph Nodes Can Be the Source of Distant Metastases in Mouse Models of Cancer Mar. 22, 2018 — A study finds that, in mouse models, cancer cells from metastatic lymph nodes can escape into the circulation by invading nodal blood vessels, leading to the development of metastases in other parts ... read more
  29. Compound to Prevent Breast Cancer Cells from Activating in Brain Mar. 22, 2018 — Researchers have used computer modeling to find an existing investigational drug compound for leukemia patients to treat triple negative breast cancer once it spreads to the ... read more
  30. Scientists Caution That a Rare Childhood Liver Cancer Can Spread to the Brain Mar. 19, 2018 — A new report details three cases of secondary brain tumors in people with fibrolamellar hepatocellular carcinoma. The researchers say imaging tests could improve treatment for patients whose cancer ... read more