I Wish I Could Keep Microdosing LSD

If the drug were legal, I’d be first in line

Ayelet Waldman
6 min readMay 29, 2018
Art by Jessica Siao

Some time ago, I embarked on an experiment microdosing with LSD. Though I am not a neophyte when it comes to drugs, I am not your typical psychonaut. The morning I deposited 10 micrograms of liquid LSD under my tongue was the first time I had ever tried the drug. The inside of my head has always been a place that scares me. Getting too close a look at what’s going on in there is the last thing I ever wanted.

I didn’t take the LSD because I was after spiritual transcendence. Nor was I interested in performance enhancement. I took the LSD and continued to take it for the next 30 days because I was trying to not kill myself.

I suffer from a mood disorder that has been variously diagnosed as bipolar II, cyclothymia, premenstrual dysphoric disorder, and just general bitchiness. (To be fair, the latter was an insult, not a diagnosis, though it may be the most accurate assessment of all.) At the time when I began my microdosing experiment, my medications had failed me. The reasons are complicated and described at length in the book I wrote about my microdosing experiment, A Really Good Day: How Microdosing Made a Mega Difference in My Mood, My Marriage, and My Life, but suffice it to say that everything goes to hell when you hit middle age, even (or maybe…

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Ayelet Waldman

Novelist, television writer, proud and loyal member of the Writer Guild of America.