Is Aspartame bad for you?

David Gamble
Science and Critical Thinking
6 min readSep 5, 2022

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When it comes to Aspartame, I have a bit of a conflict of interest. I drink a can or two of Diet Coke per day, and so I seriously have to examine my thinking and ask if confirmation bias is kicking in when writing to assure you that Aspartame is totally safe.

Is Aspartame as a suger alternative really safe or are there serious health concerns?

Let’s see.

The Discovery

The accidental discovery of this artificial sweetener is something that causes me to pause with a “Wait, he did what!” retort.

The backstory here is that in 1965 chemist James M. Schlatter was working on generating a tetrapeptide of the hormone gastrin. At that time it was part of some research he was doing into an anti-ulcer drug candidate, and so as one of the intermediate steps he synthesized aspartame.[1]. The discovery happened when he attempted to pick up some paper by licking his finger and discovered a sweet taste. It was the Aspartame that had contaminated his hands.

My immediate thought on hearing about this is to seriously wonder how a guy who was randomly licking his unwashed fingers in a chemistry lab after contaminating them managed to not die an early and rather sudden death.

Seriously, who actually does this?

Dire Warnings about…

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David Gamble
Science and Critical Thinking

Blogger and writer with a keen interest in science, skepticism, critical thinking, and many other weird and whacky topics.