Street Science
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Street Science

Correlation (II): How To Spot The Surrogate Endpoint Problem?

This problem has no known solution!

Correlation (II): How To Spot The Surrogate Endpoint Problem? — A cartoon illustration showing two stick figures. On the left, a happy stick figure says, “To complete the study, we have to wait for you to die!” On the right, a sad stick figure with a green face seems uncomfortable with the conversation.

When it comes to the notion of correlation, the surrogate endpoint problem presents a very persistent challenge that no one has solved until today. It subtly catches researchers off guard and leads to false conclusions and decisions.

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