The Neuroscientific Case for Facing Your Fears

A new study shows that mice have to remember their phobias if they are to lose them effectively

Ed Yong
The Atlantic

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A mouse stares at a mousetrap. Photo: ERIC ISSELEE / DMITRIJ SKOROBOGATOV / SHUTTERSTOCK / KATIE MARTIN / THE ATLANTIC

Peter, aged 3, was scared of rabbits. So Mary Cover Jones kept bringing him rabbits.

At first, she’d take a caged rabbit up to Peter, while he ate some candy and played with other children. At first, Peter was terrified by the mere presence of a rabbit in the same room. But soon, he allowed the animal to get closer — 12 feet, then four, then three. Eventually, Peter was happy for rabbits to nibble his fingers. “The case of Peter illustrates how a fear may be removed under laboratory conditions,” Cover Jones wrote in 1924.

Cover Jones is now recognized as the “mother of behavioral therapy.” Her observations laid the groundwork for what would become known as exposure therapy — the practice of getting people to overcome their fears by facing them in controlled settings.

A century later, neuroscientists can watch how the act of facing one’s fears actually plays out inside the brain. Using gene-engineering tools, they can label the exact neurons in a mouse’s brain that store a specific fearful memory. Then, they can watch what happens when the rodent recalls those experiences.

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Ed Yong
The Atlantic

Science writer at The Atlantic. Author of I CONTAIN MULTITUDES, a New York Times bestseller on animal-microbe partnerships. https://edyong.me/