The History of Antibiotics Through the Lens of Circumcision

Ismail Badjie, PharmD
The Weekly Prescription
9 min readMar 27, 2024

The Pre-Antibiotic Era and the Emergence of Circumcision

Stepping back into the shadows of pre-antibiotic history, humanity waged a relentless struggle against an unseen microbial world. Diseases we now regard as mere inconveniences were once harbingers of doom, and the simplest wound could spell a death sentence. Amid this turbulent era, cleanliness became the shield and spear against infection. It was an epoch where the suds of soap bore the weight of lives, and the clear waters of cleanliness were as precious as any elixir of health. Practices such as circumcision, which might seem rooted in tradition, also found their rationale in the fight for hygiene, becoming intertwined with the medical theories of the time. It served as a prelude to the medical revolution that would come with the advent of antibiotics, where the scalpel would eventually yield to the pill, transforming the landscape of human health forever.

Amidst this landscape, the practice of circumcision emerged as a necessity to curb infection rates in men, which inadvertently affected women. It is important to note that circumcision was not a correction of a flaw in God’s design of the male genitalia, but rather a necessary sacrifice of skin to combat infections in a time when antibiotics did not exist.

The history of circumcision dates back to ancient times, with the earliest recorded evidence found in Egyptian tombs dating back to 2400 BCE. It was practiced for various reasons, including religious, cultural, and hygienic purposes. In some cultures, circumcision was seen as a rite of passage, marking the transition from boyhood to manhood.

Woven into the tapestry of this narrative is the African context, where circumcision transcends the boundaries of health and becomes a cultural cornerstone. In Gambia, the circumcision of boys is not only a health-conscious practice but also a deeply ingrained social tradition, symbolizing the journey into adulthood and community responsibility. Under the vast Gambian sky, where the sun scorches the earth and the baobab trees stand as silent witnesses to centuries of tradition, circumcision ceremonies are elaborate festivals of communal joy and collective guidance. Here, it embodies a social contract, an unspoken agreement passed down through generations, echoing the belief that the individual’s well-being is tied to the collective health.

This practice, deeply rooted in Gambian society, is a testament to the adaptive strategies humans developed in response to their environment. Long before the concept of germs would enter the scientific lexicon, traditional African medicine had already recognized the link between cleanliness and health. Thus, in the absence of antibiotics, circumcision was adopted as a preventive measure against infections, especially those that thrived in the warmth and humidity that characterize much of the African climate. It’s a poignant reminder that, across cultures and continents, our ancestors sought to protect and prolong life using the knowledge and tools available to them, paving the way for the future of medical science.

The Discovery of Antibiotics and Traditional African Medicine

The term “discovery” in relation to antibiotics should be used with some caution. While Alexander Fleming’s work was groundbreaking and transformative, it is important to acknowledge that the concept of using substances to fight infections was not entirely new. In fact, Africa has a rich history of using herbs and alchemist concoctions with antibiotic properties long before Fleming’s discovery.

Traditional African medicine has always placed a strong emphasis on the use of plants and herbs to treat various ailments, including infectious diseases. Across the continent, indigenous healers have developed a vast knowledge of medicinal plants, passed down through generations. Many of these plants contain compounds with antimicrobial properties, capable of fighting off harmful bacteria.

For instance, in West Africa, including The Gambia, the bark of the Cryptolepis sanguinolenta plant has been used for centuries to treat malaria and other infectious diseases. Studies have shown that this plant contains alkaloids with potent antibacterial properties. Similarly, the Garcinia kola nut, native to West and Central Africa, has been used traditionally to treat respiratory infections and has been found to contain compounds active against a range of bacteria.

In East Africa, the Warburgia ugandensis tree has been used in traditional medicine to treat a variety of infections. Its bark and leaves contain compounds that have shown antibacterial activity against several pathogens, including those causing tuberculosis and pneumonia. These are just a few examples of the many medicinal plants used across Africa that have antibiotic properties.

However, what sets Fleming’s discovery apart is the application of scientific theory and method. Fleming’s work allowed for the isolation, purification, and mass production of penicillin, making it widely accessible. This marked a shift from the use of raw plant materials to the development of standardized, quality-controlled medicines.

Fleming’s discovery also paved the way for the systematic search for new antibiotics. Following the success of penicillin, scientists began to screen thousands of microorganisms in search of new antibiotic compounds. This led to the discovery of many new classes of antibiotics, such as streptomycin, tetracycline, and chloramphenicol, each with their unique mechanisms of action and spectra of activity.

The impact of this scientific approach to antibiotic discovery cannot be overstated. It allowed for the development of drugs that were more potent, more specific, and could be produced on a large scale. This, in turn, revolutionized the treatment of infectious diseases, saving countless lives and transforming the field of medicine.

The recognition that scientific advancements in antibiotics are built upon a foundation of traditional knowledge, including the use of medicinal plants with antibiotic properties in African medicine, is crucial. However, the current misuse and abuse of antibiotics in Africa due to access without proper diagnosis and supervision have led to the emergence of antibiotic-resistant bacteria, a problem that poses a significant threat to global health, particularly in the context of sexual and reproductive health.

The emergence of antibiotic-resistant strains of sexually transmitted infections (STIs), such as gonorrhea, chlamydia, and syphilis, is making treatment increasingly difficult. The consequences of untreated STIs can be severe, leading to pelvic inflammatory disease, infertility, and an increased risk of HIV transmission. In pregnant women, untreated STIs can cause serious complications, such as stillbirth, preterm delivery, and neonatal infections. The spread of antibiotic resistant STIs could reverse decades of progress in sexual and reproductive health.

Moreover, antibiotic resistance in other bacterial infections, such as urinary tract infections (UTIs) and bacterial vaginosis, poses significant challenges for women’s health, potentially leading to serious complications.

The COVID-19 pandemic has provided a glimpse into the potential global crisis that could result from widespread antibiotic resistance. The resurgence of once-treatable diseases as deadly threats is a sobering possibility, and immediate action is necessary to prevent this from becoming a reality.

Promoting responsible antibiotic use, investing in the development of new antibiotics, and strengthening infection prevention and control measures are essential steps. Additionally, addressing the socioeconomic factors that contribute to the misuse of antibiotics in Africa, such as limited access to healthcare, inadequate diagnostic facilities, and the availability of antibiotics without prescription, is crucial.

The potential global crisis of antibiotic resistance, particularly in the context of sexual and reproductive health, requires immediate action and global cooperation. By learning from traditional knowledge, promoting responsible antibiotic use, and addressing underlying socioeconomic factors, we can work towards a future where antibiotics remain effective and continue to save lives.

The Complexities of Female Circumcision and Sexual Health

While circumcision in males was historically rooted in efforts to reduce infections and enhance hygiene, female circumcision has complex implications for women’s health. Female circumcision, involving the alteration or removal of parts of the external genitalia, is a practice mired in deep cultural traditions. It can lead to an increased susceptibility to infections due to the creation of scar tissue, which can harbor bacteria and lead to recurrent urinary tract infections, bacterial vaginosis, and other vaginal infections.

Furthermore, the disruption of the natural genital structure can lead to complications in the natural cleaning process of the female genitalia. The delicate pH balance can be upset, increasing the risk of infections. The removal of protective tissue makes the transmission of sexually transmitted infections (STIs) more likely during intercourse.

In the context of sexual health, women who have undergone circumcision may face challenges. The alteration of sensitive genital tissue can affect the natural experience of intimacy and pleasure, which are fundamental aspects of human sexuality. Certain types of female genital circumcision that involve stitching or partial closure of the vaginal opening can compromise the natural elasticity of the tissue. During moments of intimacy, this alteration can lead to painful tearing, recurrent bleeding, and an increased risk of infections due to the compromised integrity of the genital tissue.

These procedures, unfortunately, can reflect a historical misunderstanding of female sexuality and reproductive health, often exacerbating gender inequalities.

The sexual and reproductive health of women has been a source of wonder and misunderstanding for men throughout history. In the past, even clitoral orgasms in women were sometimes deemed a manifestation of madness. Ironically, it is often the man’s penis that has been the greatest source of misery for women, both figuratively, in terms of sexually transmitted infections or unsupported pregnancies and parenthood, and literally, as men often prioritize their own sexual vitality, with their ego and self-esteem tied to their ability to perform sexually with climax always guaranteed.

The sexual wellness and erectile dysfunction market is a lucrative one, with men willing to go to great lengths to maintain their sexual prowess. However, it is important to remember that true sexual health and fulfillment lie in mutual respect, communication, and understanding between partners.

Conclusion: Lessons, Reflections, and the Path Forward

As we reflect on the history of antibiotics and circumcision, we must also consider the broader cultural context in which these practices exist.

The power of culture and tradition can be so deeply ingrained that even women, often the victims of harmful practices, can become complicit in perpetuating them. When these practices are reinforced by influential figures, it creates a formidable barrier to change. This vicious cycle, where women are both victims and perpetrators, is a testament to the insidious nature of deeply entrenched cultural norms. Challenging harmful practices requires not only confronting male-dominated power structures but also empowering women to break free from tradition and become agents of change.

Our cultural tapestry is richly beautiful, woven with traditions that define, shape, and color our collective identity. From vibrant festivals that echo the joy of our communities to the wisdom passed down through generations, our heritage is a source of immense pride and joy. However, this cultural legacy does not demand unyielding allegiance to practices that harm us. Instead, it offers the fluidity to evolve. When new information presents itself, a progressive society possesses the strength and wisdom to reassess and redirect the course of its actions. This ability to adapt and transform is the essence of human development, a force that has propelled civilizations forward throughout history. Embracing change that enriches well-being is not a betrayal of our past — it is, instead, an affirmation of our commitment to the future, ensuring that our culture remains as nurturing as it is ancient, and as dynamic as it is rooted.

We must collectively re-examine cultural practices that may cause harm, particularly to women and girls. By approaching these issues with empathy, understanding, and a willingness to adapt, we can build a future where health and well-being are prioritized for all.

As we close, I invite you to imagine a world where women rulers of a land gather to decide on a law that has the potential to diminish the sexual prowess of men, perhaps to tame a perceived propensity for violence and aggression. How would we, as men, react to such a proposal? This thought experiment serves as a powerful reminder of the importance of bodily autonomy and the right to make decisions about one’s own health and well-being, regardless of gender.

In the end, the path forward is clear: we must work together to create a world where every individual, regardless of their gender or cultural background, has access to the knowledge, resources, and support they need to make informed decisions about their health and well-being. By doing so, we can build a future where the legacy of antibiotics and circumcision is one of progress, empowerment, and hope for all.

In peace, love, and good health,

Dr. IDB.

For more information, follow the work of Dr. Badjie and his Innovarx WOW team on www.igh.gm and on social media @innovarxglobal or call +2866200. Ismail is also the author of newly released book “LIFE AS A HYPHEN” available at Timbooktoo Bookstore and Kairo Café (Fajara).

Disclaimer: The information provided in this article is for general understanding and does not constitute a diagnosis. For specific concerns or detailed health advice, always consult your designated healthcare professional.

--

--