Karl SebbyTileDB in genomics: getting started with TileDB-VCF to store and query genomic variant dataTileDB describes itself as “The Universal Database” for all data and cites use cases in finance, LiDAR, imaging, and genomics on its…May 24, 20221May 24, 20221
Karl SebbyWhy hasn’t bioinformatics been democratized yet? 5 reasons.“Democratization of bioinformatics.” I’ve seen the phrase many times. The argument usually goes something like this:Apr 28, 2022Apr 28, 2022
Karl SebbyValidating bioinformatics methods: How reproducing results identified what I did wrongA recommended way to validate or verify genomic lab tests is to share samples between labs and ensure that the results are comparable. On…Feb 10, 2022Feb 10, 2022
Karl SebbyWhat is the cost of bioinformatics? A look at bioinformatics pricing and costsChances are, you might not have a clear picture of what your genomics analyses cost; particularly on the individual job or sample level…Feb 2, 2022Feb 2, 2022
Karl SebbyDemystifying benchmarking: A guide to germline variant calling metricsWe recently developed and published a germline variant calling pipeline on Truwl that follows the GA4GH best practices using hap.py. This…Dec 13, 2021Dec 13, 2021
Karl SebbyA brief overview of benchmarking in genomicsThere’s always a steady stream of genomics benchmarking papers coming out, but recently it’s been like drinking out of a firehose. But if…Nov 12, 2021Nov 12, 2021
Karl SebbyWhy make computational methods openly accessible?We’ve put an emphasis on making bioinformatics methods on Truwl as open and accessible as possible. That means being able to see content…Oct 28, 2021Oct 28, 2021
Karl SebbyProcessing 200 RNA-seq samples over the weekendWhen Feng Liu needed to process data from 200 ATAC-seq and 200 RNA-seq experiments he turned to Truwl to get it done.Oct 20, 2021Oct 20, 2021
Karl SebbyAccessible and uniform benchmarkingDo you remember GCAT? You know what I’m talking about, the Genome Comparison and Analytic Testing platform. If you remember…Oct 14, 2021Oct 14, 2021
Karl SebbyTurning the ENCODE pipelines into community resourcesAfter the completion of the Human Genome Project (HGP) in 2003 which deciphered the order of bases in the human genome — represented by…Oct 13, 2021Oct 13, 2021
