It was a difficult decision, but I had to do it. I fired Evening Bryan.
To be fair, Evening Bryan (5pm-10pm) faced a formidable challenge in his daily shift: deciding when, what and how much to eat. For ten years, Evening Bryan overate and gained more than fifty pounds, fueling relentless shame, guilt and malaise. Every night, he failed the marshmallow test; temporarily discounting the future in favor of the here, the now, the carbs, and the sugar.
His behavior had devastating ripple effects on the other Bryans. The excessive nighttime food consumption made quality sleep nearly impossible for Nighttime Bryan (10pm - 6am), which caused Morning Bryan (6am-12pm) to be quite displeased because he consistently felt tired, irritable and unprepared for the demands of life. …
Subject: Mainframes to PCs. $1B genome to $1k. The brain and mind are next.
What a fun week it has been! After four years quietly building, we pulled back the curtains at Kernel, revealing how our brain recording hardware will replace room-sized machines.
We’ve seen this before. Mainframes became PCs. The $1B genome became $1k. The brain and mind are next.
A coronavirus has ravaged our planet. Humanity brought to its knees by 29,829 nucleotides of “bad news wrapped in a protein.” In 2014, Jeff Klunzinger and I designed OS Fund to build a Global Biological Immune system poised to combat pandemics, climate change, famine.
OS Fund companies have mobilized, like our body’s immune response:
Navy & Air Force: Nanoly.
Here is what each is doing.
Numat makes MOFs, a miracle nanomaterial which can be woven into fabric. Designed atom-by-atom so well it can filter heavy metal ions from water and be made into nanoporous masks and filters, which the DoD noticed, to make the next gen of personal protection equipment (PPE). …
Covid-19 is like a surprise school exam, that your teacher told you would be coming. It was in the syllabus, the teacher reminded the class several times, and yet when it arrives, it’s abrupt chaos! It is tough being human.
I am eager to learn best practices from others re: Covid-19. Here is what we did at Kernel this week:
Daily Covid-19 strategy planning
Each morning, company leaders and I met to digest daily news, the most recent science and recommendations to determine the day’s specific actions. Circumstances were changing, our company goals remained the same.
We had an all-company meeting on Monday to level set…
The other night my teenage boys asked me what was on my mind (likely looking for material to make fun of me. Just kidding, they’re thoughtful kids).
Instead of trying to “kid proof” my thoughts or rush the conversation, I wrote them this letter. First, to explain that I’m consumed by how we think about and where we look for answers to the biggest questions of our time (listed below), and second, to propose an alternative way of finding answers (hint: I found inspiration in an amoeba).
OS Fund portfolio company Pivot Bio made an exciting announcement that is a proof point of our thesis: companies commercializing deep tech represent solutions to our most pressing challenges as well as outsize returns. The previous era was built on silicon, the future will be built on atoms, molecules, organisms and complex systems.
Pivot Bio’s flagship product, PROVEN™, is a microbe-based alternative to nitrogen-based fertilizer. An alternative is critical: half of our world’s food supply is dependent on synthetic nitrogen fertilizer, yet it has serious environmental impacts. …
A month ago I finished reading Why We Sleep. Not only did I become convinced that getting high-quality sleep is the best protector and enhancer of health and cognition, but it is also the most underappreciated.
I’m shocked that sleep hygiene is not a global priority, and even more irate that my three children are expected to maintain school schedules that hinder adolescent development and contribute to mental illness. The science is sound.
Over the past few weeks, I’ve worked to systematically optimize my sleep and have experienced significant gains, ranging from a 40% to 157% increase in deep sleep! …
This article is part of a series about how OS Fund (OSF) companies are radically redefining our future by rewriting the operating systems of life. Or as we prefer to think about it: Step 1: Put a dent into the universe. And Step 2: Rewrite the universe. You can see the full OSF collection here and read more about Building a Biological Immune System.
In contemplating the future, I love imagining how our daily lives today will be thought of in the future. What appears sci-fi to us today but will be “normal” 50 years from now? …
There’s money to be made and lives to be saved with the tiny stuff that’s all around us.
Saving the world (or some subset of people in it) is in vogue among the world’s wealthiest.
Jeff Bezos has a rocket company, Blue Origin. Bezos believes our future is extraterrestrial, and his rocket company exists because he thinks the price for getting anything off this rock is too damn high.
Bezos is not alone. Elon Musk is also building huge, reusable rockets. He wants to see humans fly to Mars, initially on a lark but eventually for forever.
This type of long-term thinking about the future of our species coupled with serious investment is important. But Bezos and Musk (and most other investors) are missing the most significant — and smallest — technological opportunity to save humanity. …
I’m consumed with inquiring about what our cognitive existence could be like in 20, 50, and 100 years.
My take on where we’re heading: an evolutionary transition on a scale like the planet experienced from early hominids 2 million years ago to us today. Just like that last leap, this next evolutionary chapter will be sufficiently large that Earth’s minds don’t yet have words or concepts to explain it. It simply sits beyond our imagination.
Since we can’t see it, we can’t JFK it (go to the moon), MLK it (have a dream), or Babe Ruth it (call the home run). …